Systems Biology

Systems Biology is a new designation of an old concept; namely, no part of the body functions independently from other parts.  In order to understand how something works or why it doesn't work, one should look at all of the potential interactions both internally and externally.  In an era in which specialization is the emphasis, the system approach is counter-culture or at best suggests that a diverse team approach is necessary.

In the current context, IPRS believes that developing tools to understand system interaction and behavior will be the best strategy to understand disease processes and to evaluate treatment alternatives, especially alternatives that have minimal side effects.  Our approach to understanding systems is to use computer models to help us determine the likely sensitive control points, those points at which if we make alterations, will have a significant impact on the outcome.  For this perspective systems biology and its subset computational biology relies heavily upon disciplines outside of biology such as control theory, optimization algorithms, intelligent software and mathematical representations and simulations.

For more details on biological systems contact us regarding web content that has yet to be posted on systems.  See an introduction on mathematical modeling in biological systems .

Systems and modeling pages are under development.  See the following:

•     General Regulatory Schemes

•     Regulatory Scheme Specific to Calcium

•     Alternate Schema for Calcium Regulation

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Revised: January 07, 2012